| Name | CID 2858522 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4293 |
| Prices | $139.00 |
| Sizes | 10 mg |
| Cas Number | 758679-97-9 |
| Chemical Name | 1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]ethanone |
| Formula | C28H39N3O3 |
| Molecular Weight | 465.63 |
| Purity | >98 % |
| Description | Selectively inhibits protein kinase C (PKC)-induced activation of the NF- κ B pathway (IC 50 < 0.1 μ M for PMA -stimulated IL-8 production). Inhibits antigen receptor-stimulated NF- κ B activation in chronic lymphocytic leukemia (CLL) B cells. Does not inhibit other NF- κ B pathways, including that activated by tumor necrosis factor (TNF). |
| Supplier Page | Shop |