CJ 033466

• Supplier: Tocris Bioscience
• Catalog: 3160
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 519148-48-2
• Chemical Name: 5-Amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl]-imidazo[1,2-a]pyridine-8-carboxamide
• Formula: C19H28ClN5O
• Molecular Weight: 377.91
• Purity: >98 %
• Description: Potent and selective 5-HT 4 partial agonist (EC 50 = 0.927 nM). Displays > 1000-fold selectivity for 5-HT 4 over other 5-HT and D 2 receptors. Exhibits gastroprokinetic effects in vivo following oral administration. Weakly blocks hERG (IC 50 = 2.6 μ M).

Product References

The 5-HT(4) agonists cisapride, mosapride, and CJ-033466, a Novel potent - The 5-HT(4) agonists cisapride, mosapride, and CJ-033466, a Novel potent

Toga T, Kohmura Y, Kawatsu R. J Pharmacol Sci. 2007 Oct;105(2):207-10. Epub 2007 Oct 6.

5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2-alpha]p - 5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2-alpha]p

Mikami T, Ochi Y, Suzuki K, Saito T, Sugie Y, Sakakibara M. J Pharmacol Exp Ther. 2008 Apr;325(1):190-9.