CK 869

Name CK 869
Supplier Tocris Bioscience
Catalog 3950
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 388592-44-7
Chemical Name 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone
Formula C17H16BrNO3S
Molecular Weight 394.28
Purity >98 %
Description Inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization (IC 50 = 11 μ M). Does not inhibit budding or fission yeast Arp2/3 complexes.
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Product References

Characterization of two classes of small molecule inhibitors of Arp2/3 complex. - Characterization of two classes of small molecule inhibitors of Arp2/3 complex.

Nolen BJ, Tomasevic N, Russell A, Pierce DW, Jia Z, McCormick CD, Hartman J, Sakowicz R, Pollard TD. Nature. 2009 Aug 20;460(7258):1031-4.

Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by - Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by

Hetrick B, Han MS, Helgeson LA, Nolen BJ. Chem Biol. 2013 May 23;20(5):701-12.