| Name | CL 218872 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 5329 |
| Prices | $95.00, $349.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 66548-69-4 |
| Chemical Name | 3-Methyl-6-[-3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine |
| Formula | C13H9F3N4 |
| Molecular Weight | 278.24 |
| Purity | >99 % |
| Description | Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo . |
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Squires RF, Benson DI, Braestrup C, Coupet J, Klepner CA, Myers V, Beer B. Pharmacol Biochem Behav. 1979 May;10(5):825-30.
Sieghart W. Pharmacol Rev. 1995 Jun;47(2):181-234.