CL 316243 disodium salt

• Supplier: Tocris Bioscience
• Catalog: 1709
• Prices: $185.00, $755.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 151126-84-0
• Chemical Name: 5-[(2R)-2-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylicaciddisodiumsalt
• Formula: C20H18ClNNa2O7
• Molecular Weight: 465.8
• Purity: >98 %
• Description: Potent and highly selective β 3 -adrenoceptor agonist (EC 50 = 3 nM); > 10000-fold selective over β 1 and β 2 receptors. Increases brown adipose tissue thermogenesis and metabolic rate, and decreases blood insulin and glucose levels following oral administration in vivo .

Product References

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino] - Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino]

Bloom JD, Dutia MD, Johnson BD, Wissner A, Burns MG, Largis EE, Dolan JA, Claus TH. J Med Chem. 1992 Aug 7;35(16):3081-4.

Anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta - Anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta

Yoshida T, Sakane N, Wakabayashi Y, Umekawa T, Kondo M. Life Sci. 1994;54(7):491-8.

Efficacy of the beta3-adrenergic receptor agonist CL-316243 on experimental - Efficacy of the beta3-adrenergic receptor agonist CL-316243 on experimental

Woods M, Carson N, Norton NW, Sheldon JH, Argentieri TM. J Urol. 2001 Sep;166(3):1142-7.