| Name | TAT-cyclo-CLLFVY |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4822 |
| Prices | $239.00 |
| Sizes | 1 mg |
| Function Type | Inhibitor |
| Cas Number | 1446322-66-2 |
| Formula | C111H188N42O24S2 |
| Molecular Weight | 2559.1 |
| Description | Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1 α , but not HIF-2 α , with HIF-1 β (IC 50 = 1.3 μ M) . Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro . Also reduces tubularization of hypoxic HUVECs. |
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