2-CMDO

Name 2-CMDO
Supplier Tocris Bioscience
Catalog 5242
Prices $139.00, $585.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 24140-98-5
Chemical Name 2-Chloro-11-(4-methylpiperazino)dibenz(Z)[b,f]oxepinmaleate
Formula C19H19ClN2O.C4H4O4
Molecular Weight 442.9
Description Dopamine D 2 -like receptor antagonist that displays some selectivity for D 4 receptors (K i values are 0.54 and 2.5 nM for D 4 and D 2 receptors respectively).
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Product References

Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene - Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene

Phillips ST, de Paulis T, Baron BM, Siegel BW, Seeman P, Van Tol HH, Guan HC, Smith HE. J Med Chem. 1994 Aug 19;37(17):2686-96.

Binding of 5H-dibenzo[a,d]cycloheptene and dibenz[b,f]oxepin analogues of - Binding of 5H-dibenzo[a,d]cycloheptene and dibenz[b,f]oxepin analogues of

Phillips ST, de Paulis T, Neergaard JR, Baron BM, Siegel BW, Seeman P, Van Tol HH, Guan HC, Smith HE. J Med Chem. 1995 Feb 17;38(4):708-14.

L-745,870 suppresses the nighttime serotonin N-acetyltransferase activity in - L-745,870 suppresses the nighttime serotonin N-acetyltransferase activity in

Zawilska JB, Rosiak J, Berezinska M, Nowak JZ. J Neural Transm. 2003 Mar;110(3):219-27.