Name | CMPD-1 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 0782 |
Prices | $169.00, $705.00 |
Sizes | 10 mg, 50 mg |
Function Type | Inhibitor |
Cas Number | 41179-33-3 |
Chemical Name | 2'-Fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide |
Formula | C22H20FNO2 |
Molecular Weight | 349.4 |
Purity | >99 % |
Description | Non-ATP-competitive, selective inhibitor of p38 α -mediated MK2a (mitogen-activated protein kinase-2a) phosphorylation (apparent K i = 330 nM). Does not inhibit p38 α -mediated phosphorylation of MBP and ATF-2. Also tubulin polymerization inhibitor. Cytotoxic in glioblastoma cells at concentrations that do not affect the MK2 pathway. |
Supplier Page | Shop |