CMPD-1

Name CMPD-1
Supplier Tocris Bioscience
Catalog 0782
Prices $169.00, $705.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 41179-33-3
Chemical Name 2'-Fluoro-N-(4-hydroxyphenyl)-[1,1'-biphenyl]-4-butanamide
Formula C22H20FNO2
Molecular Weight 349.4
Purity >99 %
Description Non-ATP-competitive, selective inhibitor of p38 α -mediated MK2a (mitogen-activated protein kinase-2a) phosphorylation (apparent K i = 330 nM). Does not inhibit p38 α -mediated phosphorylation of MBP and ATF-2. Also tubulin polymerization inhibitor. Cytotoxic in glioblastoma cells at concentrations that do not affect the MK2 pathway.
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