CNQX

• Supplier: Tocris Bioscience
• Catalog: 4642
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 115066-14-3
• Chemical Name: 6-Cyano-7-nitroquinoxaline-2,3-dione
• Formula: C9H4N4O4
• Molecular Weight: 232.16
• Purity: >99 %
• Description: Potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex. CNQX disodium salt (Cat. No. 1045) also available.

Product References

Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. - Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.

Honore T, Davies SN, Drejer J, Fletcher EJ, Jacobsen P, Lodge D, Nielsen FE. Science. 1988 Aug 5;241(4866):701-3.

Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, - Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-,

Long SK, Smith DA, Siarey RJ, Evans RH. Br J Pharmacol. 1990 Aug;100(4):850-4.

Structure-activity relationships in the development of excitatory amino acid - Structure-activity relationships in the development of excitatory amino acid

Watkins JC, Krogsgaard-Larsen P, Honore T. Trends Pharmacol Sci. 1990 Jan;11(1):25-33.

Antagonism of synaptic potentials in ventral horn neurones by - Antagonism of synaptic potentials in ventral horn neurones by

King AE, Lopez-Garcia JA, Cumberbatch M. Br J Pharmacol. 1992 Oct;107(2):375-81.