Co 102862

• Supplier: Tocris Bioscience
• Catalog: 2456
• Prices: $135.00, $569.00
• Sizes: 10 mg, 50 mg
• Function Type: Blocker
• Cas Number: 181144-66-1
• Chemical Name: 2-[[4-(4-Fluorophenoxy)phenyl]methylene]hydrazinecarboxamide
• Formula: C14H12FN3O2
• Molecular Weight: 273.26
• Purity: >99 %
• Description: Broad spectrum, state-dependent blocker of voltage-gated sodium channels. Displays ~ 80-fold higher affinity for inactivated Na + channels compared to channels in the resting state. Anticonvulsant; displays activity in rodent models of tonic/clonic and partial-complex seizures.

Product References

V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of - V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of

Ilyin VI, Hodges DD, Whittemore ER, Carter RB, Cai SX, Woodward RM. Br J Pharmacol. 2005 Mar;144(6):801-12.

Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: - Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide:

Ilyin VI, Pomonis JD, Whiteside GT, Harrison JE, Pearson MS, Mark L, Turchin PI, Gottshall S, Carter RB, Nguyen P, Hogenkamp DJ, Olanrewaju S, Benjamin E, Woodward RM. J Pharmacol Exp Ther. 2006 Sep;318(3):1083-93. Epub 2006 May 25.