Colchicine

Name Colchicine
Supplier Tocris Bioscience
Catalog 3405
Prices $115.00
Sizes 1 g
Cas Number 64-86-8
Chemical Name (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
Formula C22H25NO6
Molecular Weight 399.44
Purity >98 %
Description Plant-derived alkaloid that binds to tubulin and depolymerizes microtubules.
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Product References

Interactions of colchicine with tubulin. - Interactions of colchicine with tubulin.

Hastie SB. Pharmacol Ther. 1991;51(3):377-401.

Analysis of the colchicine-binding site of beta-tubulin. - Analysis of the colchicine-binding site of beta-tubulin.

Burns RG. FEBS Lett. 1992 Feb 10;297(3):205-8.

Identification of cysteine 354 of beta-tubulin as part of the binding site for - Identification of cysteine 354 of beta-tubulin as part of the binding site for

Bai R, Pei XF, Boye O, Getahun Z, Grover S, Bekisz J, Nguyen NY, Brossi A, Hamel E. J Biol Chem. 1996 May 24;271(21):12639-45.