Conantokin-T

Name Conantokin-T
Supplier Tocris Bioscience
Catalog 3125
Prices $299.00
Sizes 500 µg
Function Type Antagonist
Cas Number 127476-26-0
Formula C110H175N31O45S
Molecular Weight 2683.8
Description Non-competitive NMDA receptor antagonist (IC 50 = 0.4 μ M). Inhibits Ca 2+ influx and glutamate-induced toxicity in central nervous system neurons. Exhibits age-dependent physiological effects; induces a sleep-like state in young mice and hyperactivity in older mice.
Supplier Page Shop

Product References

Conantokin-T. A gamma-carboxyglutamate containing peptide with - Conantokin-T. A gamma-carboxyglutamate containing peptide with

Haack JA, Rivier J, Parks TN, Mena EE, Cruz LJ, Olivera BM. J Biol Chem. 1990 Apr 15;265(11):6025-9.

Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured - Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured

Klein RC, Galdzicki Z, Castellino FJ. Neuropharmacology. 1999 Dec;38(12):1819-29.

Amino acid determinants for NMDA receptor inhibition by conantokin-T. - Amino acid determinants for NMDA receptor inhibition by conantokin-T.

Warder SE, Blandl T, Klein RC, Castellino FJ, Prorok M. J Neurochem. 2001 May;77(3):812-22.