Congo Red

• Supplier: Tocris Bioscience
• Catalog: 2409
• Prices: $49.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 573-58-0
• Chemical Name: 3,3'-[(1,1'-Biphenyl)-4,4'-diyl-bis(2,1-diazenediyl)]bis(4-amino-1-naphthalenesulfonicacid)disodiumsalt
• Formula: C32H22N6Na2O6S2
• Molecular Weight: 696.66
• Purity: >98 %
• Description: VGlut inhibitor; decreases synaptic transmission in the dentate gyrus. Also an amyloid fibril-binding dye; inhibits Fib-beta A neurotoxicity by inhibiting fibril formation or by binding to preformed fibrils. Also inhibits the pancreatic islet cell toxicity of diabetes-associated amylin. Excitation wavelength is 497 nm.

Product References

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo - Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo

Lorenzo A, Yankner BA. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12243-7.

Modulation of hippocampal synaptic transmission by the kynurenine pathway member - Modulation of hippocampal synaptic transmission by the kynurenine pathway member

Neale SA, Copeland CS, Uebele VN, Thomson FJ, Salt TE. Neuropsychopharmacology. 2013 May;38(6):1060-7.

Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent - Effect of VGLUT inhibitors on glutamatergic synaptic transmission in the rodent

Neale SA, Copeland CS, Salt TE. Neurochem Int. 2014 Jul;73:159-65.