α -Conotoxin AuIB

• Supplier: Tocris Bioscience
• Catalog: 5167
• Prices: $345.00
• Sizes: 500 µg
• Function Type: Antagonist
• Cas Number: 216299-21-7
• Formula: C65H89N17O21S4
• Molecular Weight: 1572.76
• Description: Selective antagonist of α 3 β 4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including α 2 β 2, α 2 β 4, α 3 β 2, α 4 β 2, α 4 β 4 and α 1 β 1 γ δ .

Product References

alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine - alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine

Luo S, Kulak JM, Cartier GE, Jacobsen RB, Yoshikami D, Olivera BM, McIntosh JM. J Neurosci. 1998 Nov 1;18(21):8571-9.

Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit - Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit

Nai Q, McIntosh JM, Margiotta JF. Mol Pharmacol. 2003 Feb;63(2):311-24.

An alpha3beta4 subunit combination acts as a major functional nicotinic - An alpha3beta4 subunit combination acts as a major functional nicotinic

Park KS, Cha SK, Kim MJ, Kim DR, Jeong SW, Lee JW, Kong ID. Pflugers Arch. 2006 Sep;452(6):775-83. Epub 2006 May 20.