α -Conotoxin PnIA

Name α -Conotoxin PnIA
Supplier Tocris Bioscience
Catalog 3121
Prices $385.00
Sizes 500 µg
Function Type Antagonist
Cas Number 705300-84-1
Formula C65H95N19O22S4
Molecular Weight 1622.82
Description Selective antagonist of α 3 β 2 nAChR receptors (IC 50 values are 9.56 and 252 nM for α 3 β 2 and α 7 receptors respectively).
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Product References

New mollusc-specific alpha-conotoxins block Aplysia neuronal acetylcholine - New mollusc-specific alpha-conotoxins block Aplysia neuronal acetylcholine

Fainzilber M, Hasson A, Oren R, Burlingame AL, Gordon D, Spira ME, Zlotkin E. Biochemistry. 1994 Aug 16;33(32):9523-9.

Single-residue alteration in alpha-conotoxin PnIA switches its nAChR subtype - Single-residue alteration in alpha-conotoxin PnIA switches its nAChR subtype

Luo S, Nguyen TA, Cartier GE, Olivera BM, Yoshikami D, McIntosh JM. Biochemistry. 1999 Nov 2;38(44):14542-8.

Identification of residues that confer alpha-conotoxin-PnIA sensitivity on the - Identification of residues that confer alpha-conotoxin-PnIA sensitivity on the

Everhart D, Reiller E, Mirzoian A, McIntosh JM, Malhotra A, Luetje CW. J Pharmacol Exp Ther. 2003 Aug;306(2):664-70. Epub 2003 May 6.