CP 316819

• Supplier: Tocris Bioscience
• Catalog: 3023
• Prices: $205.00, $845.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 186392-43-8
• Chemical Name: 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide
• Formula: C21H22ClN3O4
• Molecular Weight: 415.87
• Purity: >98 %
• Description: Selective glycogen phosphorylase inhibitor [IC 50 values are 0.017 and 0.034 μ M against human skeletal muscle glycogen phosphorylase a (huSMGPa) and liver glycogen phosphorylase a (huLGPa) respectively]. Antihyperglycemic agent.

Product References

Glycogen phosphorylase inhibition in type 2 diabetes therapy: a systematic - Glycogen phosphorylase inhibition in type 2 diabetes therapy: a systematic

Baker DJ, Timmons JA, Greenhaff PL. Diabetes. 2005 Aug;54(8):2453-9.

Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is - Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is

Freeman S, Bartlett JB, Convey G, Hardern I, Teague JL, Loxham SJ, Allen JM, Poucher SM, Charles AD. Br J Pharmacol. 2006 Nov;149(6):775-85. Epub 2006 Oct 3.

Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with - Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with

Suh SW, Bergher JP, Anderson CM, Treadway JL, Fosgerau K, Swanson RA. J Pharmacol Exp Ther. 2007 Apr;321(1):45-50. Epub 2007 Jan 24.