CP 809101 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2729
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 1215721-40-6
• Chemical Name: 2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazinehydrochloride
• Formula: C15H17N4OCl.HCl
• Molecular Weight: 341.24
• Purity: >99 %
• Description: Potent and selective 5-HT 2C receptor agonist (pEC 50 values are 9.96, 7.19 and 6.81 for human 5-HT 2C , 5-HT 2B and 5-HT 2A receptors respectively). Displays antipsychotic activity; suppresses condition avoidance responding (CAR) and inhibits PCP and amphetamine-stimulated hyperactivity in rats following subcutaneous administration.

Product References

Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel - Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel

Kalgutkar AS, Dalvie DK, Aubrecht J, Smith EB, Coffing SL, Cheung JR, Vage C, Lame ME, Chiang P, McClure KF, Maurer TS, Coelho RV Jr, Soliman VF, Schildknegt K. Drug Metab Dispos. 2007 Jun;35(6):848-58. Epub 2007 Mar 7.

CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of - CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of

Siuciak JA, Chapin DS, McCarthy SA, Guanowsky V, Brown J, Chiang P, Marala R, Patterson T, Seymour PA, Swick A, Iredale PA. Neuropharmacology. 2007 Feb;52(2):279-90. Epub 2006 Sep 1.

Design, synthesis, and pharmacological characterization of N- and O-substituted - Design, synthesis, and pharmacological characterization of N- and O-substituted

Jensen AA, Plath N, Pedersen MH, Isberg V, Krall J, Wellendorph P, Stensbol TB, Gloriam DE, Krogsgaard-Larsen P, Frolund B. J Med Chem. 2013 Feb 14;56(3):1211-27.