CP 93129 dihydrochloride

Name CP 93129 dihydrochloride
Supplier Tocris Bioscience
Catalog 3041
Prices $159.00, $665.00
Sizes 10 mg, 50 mg
Function Type Agonist
Cas Number 879089-64-2
Chemical Name 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-onedihydrochloride
Formula C12H13N3O.2HCl
Molecular Weight 288.18
Description Potent and highly selective 5-HT 1B agonist (K i values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT 1B , 5-HT 1D , 5-HT 1A , 5-HT 1c and 5-HT 2 , respectively). Reduces food intake and decreases body weight in rats.
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Product References

Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial - Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial

Lee MD, Aloyo VJ, Fluharty SJ, Simansky KJ. Psychopharmacology (Berl). 1998 Apr;136(3):304-7.

Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture - Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture

Hamid E, Church E, Wells CA, Zurawski Z, Hamm HE, Alford S. J Neurosci. 2014 Jan 1;34(1):260-74.