CP 96345

• Supplier: Tocris Bioscience
• Catalog: 4236
• Prices: $205.00, $845.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 132746-60-2
• Chemical Name: (2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine
• Formula: C28H32N2O
• Molecular Weight: 412.57
• Purity: >98 %
• Description: Potent and selective non-peptide NK 1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo .

Product References

A potent nonpeptide antagonist of the substance P (NK1) receptor. - A potent nonpeptide antagonist of the substance P (NK1) receptor.

Snider RM, Constantine JW, Lowe JA 3rd, Longo KP, Lebel WS, Woody HA, Drozda SE, Desai MC, Vinick FJ, Spencer RW, et al.. Science. 1991 Jan 25;251(4992):435-7.

The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of - The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of

Lembeck F, Donnerer J, Tsuchiya M, Nagahisa A. Br J Pharmacol. 1992 Mar;105(3):527-30.

Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from - Neurokinin-1 receptor antagonists CP-96,345 and L-733,060 protect mice from

Bang R, Sass G, Kiemer AK, Vollmar AM, Neuhuber WL, Tiegs G. J Pharmacol Exp Ther. 2003 Apr;305(1):31-9.