CPCCOEt

• Supplier: Tocris Bioscience
• Catalog: 3417
• Prices: $149.00, $629.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 179067-99-3
• Chemical Name: 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylateethylester
• Formula: C13H13NO4
• Molecular Weight: 247.25
• Purity: >99 %
• Description: hmGlu 1 subtype-selective non-competitive antagonist (IC 50 = 6.5 μ M). Has no agonist or antagonist activity at hmGlu 2, 4a, 5a, 7b, 8a or ionotropic receptors at concentrations of up to 100 μ M.

Product References

Reversible and non-competitive antagonist profile of CPCCOEt at the human type - Reversible and non-competitive antagonist profile of CPCCOEt at the human type

Hermans E, Nahorski SR, Challiss RA. Neuropharmacology. 1998 Dec;37(12):1645-7.

CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits - CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits

Litschig S, Gasparini F, Rueegg D, Stoehr N, Flor PJ, Vranesic I, Prezeau L, Pin JP, Thomsen C, Kuhn R. Mol Pharmacol. 1999 Mar;55(3):453-61.