m -CPP hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 0173
• Prices: $59.00
• Sizes: 1 g
• Function Type: Agonist
• Cas Number: 13078-15-4
• Chemical Name: 1-(3-Chlorophenyl)piperazinehydrochloride
• Formula: C10H13ClN2.HCl
• Molecular Weight: 233.14
• Purity: >99 %
• Description: 5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .

Product References

Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine - Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine

Lucki I, Ward HR, Frazer A. J Pharmacol Exp Ther. 1989 Apr;249(1):155-64.

m-CPP: a tool for studying behavioural responses associated with 5-HT1c - m-CPP: a tool for studying behavioural responses associated with 5-HT1c

Curzon G, Kennett GA. Trends Pharmacol Sci. 1990 May;11(5):181-2.

International Union of Pharmacology classification of receptors for - International Union of Pharmacology classification of receptors for

Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP. Pharmacol Rev. 1994 Jun;46(2):157-203.

Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and - Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and

Porter RH, Benwell KR, Lamb H, Malcolm CS, Allen NH, Revell DF, Adams DR, Sheardown MJ. Br J Pharmacol. 1999 Sep;128(1):13-20.