CPPG

• Supplier: Tocris Bioscience
• Catalog: 1265
• Prices: $169.00, $705.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 183364-82-1
• Chemical Name: (RS)-α-Cyclopropyl-4-phosphonophenylglycine
• Formula: C11H14NO5P
• Molecular Weight: 271.21
• Purity: >98 %
• Description: Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K B = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .

Product References

Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic - Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic

Jane DE, Thomas NK, Tse HW, Watkins JC. Neuropharmacology. 1996;35(8):1029-35.

The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a - The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a

Toms NJ, Jane DE, Kemp MC, Bedingfield JS, Roberts PJ. Br J Pharmacol. 1996 Nov;119(5):851-4.