CRANAD 2

• Supplier: Tocris Bioscience
• Catalog: 3605
• Prices: $255.00
• Sizes: 10 mg
• Cas Number: 1193447-34-5
• Chemical Name: (T-4)-[(1E,6E)-1,7-Bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoroboron
• Formula: C23H25BF2N2O2
• Molecular Weight: 410.26
• Purity: >98 %
• Description: Near-infrared probe that binds to A β 40 aggregates (K d = 38 nM) and elicits an emission blue shift. Shown to bind to plaques in APP-PS1 transgenic mice, in vitro . Detects senile plaques in 19-month-old Tg2576 mice in vivo . Penetrates the blood-brain barrier.

Product References

Design, synthesis, and testing of difluoroboron-derivatized curcumins as - Design, synthesis, and testing of difluoroboron-derivatized curcumins as

Ran C, Xu X, Raymond SB, Ferrara BJ, Neal K, Bacskai BJ, Medarova Z, Moore A. J Am Chem Soc. 2009 Oct 28;131(42):15257-61.

Non-conjugated small molecule FRET for differentiating monomers from higher - Non-conjugated small molecule FRET for differentiating monomers from higher

Ran C, Zhao W, Moir RD, Moore A. PLoS One. 2011 Apr 29;6(4):e19362.