| Name | Cryptotanshinone |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4975 |
| Prices | $129.00, $535.00 |
| Sizes | 10 mg, 50 mg |
| Cas Number | 35825-57-1 |
| Chemical Name | 1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione |
| Formula | C19H20O3 |
| Molecular Weight | 296.36 |
| Purity | >98 % |
| Description | Major tanshinone isolated from Salvia miltiorrhiza that exhibits multiple activities. Exhibits antitumor activity via inhibition STAT3 activity (IC 50 = 4.6 μ M). Displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also improves cognitive impairment in Alzheimer's disease transgenic mice by inhibition of acetylcholinesterase (IC 50 = 4.09 μ M) and reduction in A β peptide generation. |
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Kim EJ, Jung SN, Son KH, Kim SR, Ha TY, Park MG, Jo IG, Park JG, Choe W, Kim SS, Ha J. Mol Pharmacol. 2007 Jul;72(1):62-72. Epub 2007 Apr 11.
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