| Name | CTA 056 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4543 |
| Prices | $245.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 1265822-30-7 |
| Chemical Name | 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one |
| Formula | C35H34N6O |
| Molecular Weight | 554.68 |
| Purity | >98 % |
| Description | Interleukin-2-inducible T-cell kinase (ITK) inhibitor (IC 50 values are 0.1, 0.4 and 5 μ M for ITK, BTK and ETK, respectively). Inhibits growth of cancer cells expressing ITK, including MOLT-4 and Jurkat cells in vitro . Induces apoptosis in Jurkat cells. Inhibits MOLT-4 xenograft tumor growth in mice. |
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