| Name | CVT 10216 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1710 |
| Prices | $185.00, $755.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 1005334-57-5 |
| Chemical Name | 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]benzoicacid |
| Formula | C24H19NO7S |
| Molecular Weight | 465.48 |
| Purity | >98 % |
| Description | Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC 50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). Exhibits anxiolytic effects in rat models. |
| Supplier Page | Shop |
Overstreet DH, Knapp DJ, Breese GR, Diamond I. Pharmacol Biochem Behav. 2009 Dec;94(2):255-61.
Yao L, Fan P, Arolfo M, Jiang Z, Olive MF, Zablocki J, Sun HL, Chu N, Lee J, Kim HY, Leung K, Shryock J, Blackburn B, Diamond I. Nat Med. 2010 Sep;16(9):1024-8.