CX 614

• Supplier: Tocris Bioscience
• Catalog: 2980
• Prices: $155.00, $645.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 191744-13-5
• Chemical Name: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one
• Formula: C13H13NO4
• Molecular Weight: 247.25
• Purity: >99 %
• Description: AMPAkine; positive allosteric modulator of AMPA. Prototypical benzamide which occupies subsite A only. Modulates channel deactivation and desensitization.

Product References

Stable expression of recombinant AMPA receptor subunits: binding affinities and - Stable expression of recombinant AMPA receptor subunits: binding affinities and

Hennegriff M, Arai A, Kessler M, Vanderklish P, Mutneja MS, Rogers G, Neve RL, Lynch G. J Neurochem. 1997 Jun;68(6):2424-34.

Structural and functional analysis of two new positive allosteric modulators of - Structural and functional analysis of two new positive allosteric modulators of

Timm DE, Benveniste M, Weeks AM, Nisenbaum ES, Partin KM. Mol Pharmacol. 2011 Aug;80(2):267-80.

Functional analysis of a novel positive allosteric modulator of AMPA receptors - Functional analysis of a novel positive allosteric modulator of AMPA receptors

Harms JE, Benveniste M, Maclean JK, Partin KM, Jamieson C. Neuropharmacology. 2013 Jan;64:45-52.