Cyclophosphamide

Name Cyclophosphamide
Supplier Tocris Bioscience
Catalog 1702
Prices $59.00
Sizes 50 mg
Cas Number 50-18-0
Chemical Name 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine2-oxide
Formula C7H15Cl2N2O2P
Molecular Weight 261.09
Purity >99 %
Description Nitrogen mustard alkylating agent and prodrug. Phosphoramide mustard (active metabolite) forms DNA cross-links leading to cell death. Inhibits aldehyde dehydrogenase 1 (ALDH1) through its degradation product acrolein. Chemotherapeutic for the treatment of breast cancer; regulates Bax and Bcl-2 expression when administered with etoposide (Cat. No. 1226) in breast cancer cell lines.
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