Name | Cyclophosphamide |
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Supplier | Tocris Bioscience |
Catalog | 1702 |
Prices | $59.00 |
Sizes | 50 mg |
Cas Number | 50-18-0 |
Chemical Name | 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine2-oxide |
Formula | C7H15Cl2N2O2P |
Molecular Weight | 261.09 |
Purity | >99 % |
Description | Nitrogen mustard alkylating agent and prodrug. Phosphoramide mustard (active metabolite) forms DNA cross-links leading to cell death. Inhibits aldehyde dehydrogenase 1 (ALDH1) through its degradation product acrolein. Chemotherapeutic for the treatment of breast cancer; regulates Bax and Bcl-2 expression when administered with etoposide (Cat. No. 1226) in breast cancer cell lines. |
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