Cyprodime hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 2953
• Prices: $199.00
• Sizes: 10 mg
• Function Type: Antagonist
• Cas Number: 118111-54-9
• Chemical Name: 17-(Cyclopropylmethyl)-4,14-dimethoxymorphinan-6-onehydrochloride
• Formula: C22H29NO3.HCl
• Molecular Weight: 391.93
• Purity: >98 %
• Description: Selective μ -opioid receptor antagonist (K i values are 5.4, 244.6 and 2187 nM for μ -, δ - and κ -opioid receptors respectively). Reduces levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease.

Product References

Synthesis and biological evaluation of 14-alkoxymorphinans. 11. - Synthesis and biological evaluation of 14-alkoxymorphinans. 11.

Schmidhammer H, Jennewein HK, Krassnig R, Traynor JR, Patel D, Bell K, Froschauer G, Mattersberger K, Jachs-Ewinger C, Jura P, et al.. J Med Chem. 1995 Aug 4;38(16):3071-7.

Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro - Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro

Marki A, Monory K, Otvos F, Toth G, Krassnig R, Schmidhammer H, Traynor JR, Roques BP, Maldonado R, Borsodi A. Eur J Pharmacol. 1999 Oct 27;383(2):209-14.

Mu- and delta-opioid receptor antagonists reduce levodopa-induced dyskinesia in - Mu- and delta-opioid receptor antagonists reduce levodopa-induced dyskinesia in

Henry B, Fox SH, Crossman AR, Brotchie JM. Exp Neurol. 2001 Sep;171(1):139-46.