Cytarabine

• Supplier: Tocris Bioscience
• Catalog: 0216
• Prices: $59.00
• Sizes: 50 mg
• Cas Number: 147-94-4
• Chemical Name: 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
• Formula: C9H13N3O5
• Molecular Weight: 243.22
• Purity: >99 %
• Description: Nucleoside analog of deoxycytidine; inhibits DNA replication by incorporating into DNA (IC 50 = 0.04 μ M in L1210 and CEM cell lines). Displays no inhibitory effects on RNA synthesis. Causes S phase cell cycle arrest in ML-1 cell lines; cytotoxic in L5817Y leukemia cells. Antineoplastic and antileukemic agent.

Product References

Effect of cytarabine upon metabolism of phospholipids in leukemia L5178Y cells. - Effect of cytarabine upon metabolism of phospholipids in leukemia L5178Y cells.

Yang JL, Capizzi RL, Daniel LW, King L, Waite M. Zhongguo Yao Li Xue Bao. 1986 Jul;7(4):368-73.

Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in - Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in

Breistol K, Balzarini J, Sandvold ML, Myhren F, Martinsen M, De Clercq E, Fodstad O. Cancer Res. 1999 Jun 15;59(12):2944-9.

Pharmacodynamics of cytarabine alone and in combination with - Pharmacodynamics of cytarabine alone and in combination with

Sampath D, Cortes J, Estrov Z, Du M, Shi Z, Andreeff M, Gandhi V, Plunkett W. Blood. 2006 Mar 15;107(6):2517-24. Epub 2005 Nov 17.