Cytochalasin D

• Supplier: Tocris Bioscience
• Catalog: 5474
• Prices: $105.00, $445.00
• Sizes: 1 mg, 5 mg
• Cas Number: 22144-77-0
• Chemical Name: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione
• Formula: C30H37NO6
• Molecular Weight: 507.63
• Purity: >95 %
• Description: Potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B (Cat. No. 5474), does not inhibit monosaccharide transport across the plasma membrane.

Product References

Interaction of cytochalasin D with actin filaments in the presence of ADP and - Interaction of cytochalasin D with actin filaments in the presence of ADP and

Carlier MF, Criquet P, Pantaloni D, Korn ED. J Biol Chem. 1986 Feb 15;261(5):2041-50.

Concentration-dependent effects of cytochalasin D on tight junctions and actin - Concentration-dependent effects of cytochalasin D on tight junctions and actin

Stevenson BR, Begg DA. J Cell Sci. 1994 Mar;107 ( Pt 3):367-75.

Cytochalasin D stimulation of tyrosine phosphorylation and - Cytochalasin D stimulation of tyrosine phosphorylation and

Abedi H, Zachary I. Biochem Biophys Res Commun. 1998 Apr 28;245(3):646-50.