Dansyl-NECA

• Supplier: Tocris Bioscience
• Catalog: 0482
• Prices: $209.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 219982-12-4
• Chemical Name: 1-Deoxy-1-[6-[[6-[[[5-dimethylamino)-1-naphthalenyl]sulfonyl]amino]hexyl]amino]-9H-purin-9-yl]-N-ethyl-β-D-ribofuranuronamide
• Formula: C30H40N8O6S
• Molecular Weight: 640.75
• Purity: >99 %
• Description: Potent and selective fluorescent adenosine A 1 receptor agonist (K i values are 27, 3600 and 4300 nM for A 1 , A 3 and A 2 receptors, respectively). Permits visualization of A 1 receptors in the rat cerebellar cortex.

Product References

Fluorescent probes for adenosine receptors: synthesis and biology of - Fluorescent probes for adenosine receptors: synthesis and biology of

Macchia M, Salvetti F, Barontini S, Calvani F, Gesi M, Hamdan M, Lucacchini A, Pellegrini A, Soldani P, Martini C. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3223-8.

Fluorescent ligands for adenosine receptors. - Fluorescent ligands for adenosine receptors.

Kozma E, Jayasekara PS, Squarcialupi L, Paoletta S, Moro S, Federico S, Spalluto G, Jacobson KA. Bioorg Med Chem Lett. 2013 Jan 1;23(1):26-36.