Daunorubicin hydrochloride

Name Daunorubicin hydrochloride
Supplier Tocris Bioscience
Catalog 2096
Prices $139.00
Sizes 10 mg
Cas Number 23541-50-6
Chemical Name (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyransoyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedionehydrochloride
Formula C27H29NO10.HCl
Molecular Weight 563.99
Purity >98 %
Description Anticancer agent that is clinically used to treat nonlymphocytic leukemia. Inhibits RNA and DNA synthesis and causes DNA fragmentation in vivo . Reduces tau mRNA levels in vitro .
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Product References

Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and - Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and

Aubel-Sadron G, Londos-Gagliardi D. Biochimie. 1984 May;66(5):333-52.

A critical evaluation of the mechanisms of action proposed for the antitumor - A critical evaluation of the mechanisms of action proposed for the antitumor

Gewirtz DA. Biochem Pharmacol. 1999 Apr 1;57(7):727-41.

Signaling pathways activated by daunorubicin. - Signaling pathways activated by daunorubicin.

Laurent G, Jaffrezou JP. Blood. 2001 Aug 15;98(4):913-24.

Pharmacologic reductions of total tau levels; implications for the role of - Pharmacologic reductions of total tau levels; implications for the role of

Dickey CA, Ash P, Klosak N, Lee WC, Petrucelli L, Hutton M, Eckman CB. Mol Neurodegener. 2006 Jul 26;1:6.