DBM 1285 dihydrochloride

Name DBM 1285 dihydrochloride
Supplier Tocris Bioscience
Catalog 4417
Prices $225.00, $925.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Chemical Name N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinaminedihydrochloride
Formula C21H22FN5S.2HCl
Molecular Weight 468.42
Purity >98 %
Description p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF- α production in macrophages and in vivo . Attenuates zymosan-induced inflammation and adjuvant-induced arthritis in murine models. Orally active.
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