Desloratadine

• Supplier: Tocris Bioscience
• Catalog: 3067
• Prices: $75.00
• Sizes: 50 mg
• Function Type: Antagonist
• Cas Number: 100643-71-8
• Chemical Name: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• Formula: C19H19ClN2
• Molecular Weight: 310.82
• Purity: >99 %
• Description: High affinity histamine H 1 receptor antagonist (K i = 0.87 nM); active metabolite of loratadine (Cat. No. 1944). Anti-inflammatory.

Product References

Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists. - Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists.

Kuoppamaki M, Syvalahti E, Hietala J. Eur J Pharmacol. 1993 Apr 15;245(2):179-82.

Normethylclozapine potentiates the action of quinpirole in the 6-hydroxydopamine - Normethylclozapine potentiates the action of quinpirole in the 6-hydroxydopamine

Fox S, Brotchie J. Eur J Pharmacol. 1996 Apr 22;301(1-3):27-30.

Effects of clozapine metabolites and chronic clozapine treatment on rat brain - Effects of clozapine metabolites and chronic clozapine treatment on rat brain

Wong G, Kuoppamaki M, Hietala J, Luddens H, Syvalahti E, Korpi ER. Eur J Pharmacol. 1996 Oct 31;314(3):319-23.