Dexamethasone

• Supplier: Tocris Bioscience
• Catalog: 2166
• Prices: $75.00
• Sizes: 100 mg
• Cas Number: 50-02-2
• Chemical Name: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
• Formula: C22H29FO5
• Molecular Weight: 392.47
• Purity: >98 %
• Description: Glucocorticoid; anti-inflammatory. Reduces levels of activated NF- κ B in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. Induces differentiation of human mesenchymal stem cells (MSCs). Also induces autophagy in acute lymphoblastic leukemia (ALL) cell lines.

Product References

Effects of dexamethasone and cyclosporin A on the accumulation of eosinophils in - Effects of dexamethasone and cyclosporin A on the accumulation of eosinophils in

Teixeira MM, Williams TJ, Hellewell PG. Br J Pharmacol. 1996 May;118(2):317-24.

Dexamethasone inhibits dendritic cell maturation by redirecting differentiation - Dexamethasone inhibits dendritic cell maturation by redirecting differentiation

Matasic R, Dietz AB, Vuk-Pavlovic S. J Leukoc Biol. 1999 Dec;66(6):909-14.

Cell death induced by dexamethasone in lymphoid leukemia is mediated through - Cell death induced by dexamethasone in lymphoid leukemia is mediated through

Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Bjorklund AC, Hultenby K, Lundin J, Heyman M, Soderhall S, Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grander D. Cell Death Differ. 2009 Jul;16(7):1018-29.

Short bouts of mechanical loading are as effective as dexamethasone at inducing - Short bouts of mechanical loading are as effective as dexamethasone at inducing

Sittichokechaiwut A, Edwards JH, Scutt AM, Reilly GC. Eur Cell Mater. 2010 Jul 21;20:45-57.