Dexfenfluramine hydrochloride

Name Dexfenfluramine hydrochloride
Supplier Tocris Bioscience
Catalog 1126
Prices $59.00, $205.00
Sizes 10 mg, 50 mg
Cas Number 3239-45-0
Chemical Name (S)-N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanaminehydrochloride
Formula C12H16F3N.HCl
Molecular Weight 267.72
Description Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice.
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Product References

Neuropharmacological effects of low and high doses of repeated oral - Neuropharmacological effects of low and high doses of repeated oral

Caccia S, Confalonieri S, Bergami A, Fracasso C, Anelli M, Garattini S. Pharmacol Biochem Behav. 1997 Aug;57(4):851-6.

Influence of the 5-HT(2C) receptor antagonist SB242,084 on behaviour produced by - Influence of the 5-HT(2C) receptor antagonist SB242,084 on behaviour produced by

Higgins GA, Ouagazzal AM, Grottick AJ. Br J Pharmacol. 2001 Jun;133(4):459-66.

Chronic treatment with either dexfenfluramine or sibutramine in diet-switched - Chronic treatment with either dexfenfluramine or sibutramine in diet-switched

Bush EN, Shapiro R, Brune ME, Knourek-Segel VE, Droz BA, Fey T, Lin E, Jacobson PB. Endocrine. 2006 Apr;29(2):375-81.