| Name | Dexmedetomidine hydrochloride |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2695 |
| Prices | $169.00, $705.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 145108-58-3 |
| Chemical Name | 4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazolehydrochloride |
| Formula | C13H16N2.HCl |
| Molecular Weight | 236.74 |
| Purity | >99 % |
| Description | Active isomer of medetomidine (Cat.No. 5160), a potent, highly selective α 2 -adrenoceptor agonist (K i values are 1.08 and 1750 nM for α 2 - and α 1 -adrenoceptors respectively). Displays greater selectivity over α 1 -adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Active in vivo ; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. |
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Virtanen R, Savola JM, Saano V, Nyman L. Eur J Pharmacol. 1988 May 20;150(1-2):9-14.
Fisher B, Zornow MH, Yaksh TL, Peterson BM. Eur J Pharmacol. 1991 Jan 10;192(2):221-5.