DH 97

• Supplier: Tocris Bioscience
• Catalog: 0112
• Prices: $139.00, $565.00
• Sizes: 10 mg, 50 mg
• Function Type: Antagonist
• Cas Number: 220339-00-4
• Chemical Name: N-Pentanoyl-2-benzyltryptamine
• Formula: C22H26N2O
• Molecular Weight: 334.46
• Description: A relatively potent MT 2 melatonin receptor antagonist (pK i value = 8.03), displaying 89- and 229-fold selectivity over MT 1 and GPR50 (melatonin-related orphan receptor) respectively.

Product References

Comparison of the structure-activity relationships of melatonin receptor agonists - Comparison of the structure-activity relationships of melatonin receptor agonists

Teh MT, Sugden D. Naunyn Schmiedebergs Arch Pharmacol. 1998 Nov;358(5):522-8.

Molecular and pharmacological evidence for MT1 melatonin receptor subtype in the - Molecular and pharmacological evidence for MT1 melatonin receptor subtype in the

Ting KN, Blaylock NA, Sugden D, Delagrange P, Scalbert E, Wilson VG. Br J Pharmacol. 1999 Jun;127(4):987-95.