( RS )-3,5-DHPG

• Supplier: Tocris Bioscience
• Catalog: 0839
• Prices: $65.00, $139.00, $585.00
• Sizes: 1 mg, 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 19641-83-9
• Chemical Name: (RS)-3,5-Dihydroxyphenylglycine
• Formula: C8H9NO4
• Molecular Weight: 183.16
• Purity: >99 %
• Description: Selective group I metabotropic glutamate receptor agonist which activates both mGlu 1 and mGlu 5 . Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. ( S )-3,5-DHPG (Cat. No. 0805) also available.

Product References

3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate - 3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate

Ito I, Kohda A, Tanabe S, Hirose E, Hayashi M, Mitsunaga S, Sugiyama H. Neuroreport. 1992 Nov;3(11):1013-6.

Pharmacological characterization of metabotropic glutamate receptors coupled to - Pharmacological characterization of metabotropic glutamate receptors coupled to

Pellegrini-Giampietro DE, Torregrossa SA, Moroni F. Br J Pharmacol. 1996 Jun;118(4):1035-43.

The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 - The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1

Palmer MJ, Irving AJ, Seabrook GR, Jane DE, Collingridge GL. Neuropharmacology. 1997 Nov-Dec;36(11-12):1517-32.

Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group - Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group

Mistry R, Golding N, Challiss RA. Br J Pharmacol. 1998 Feb;123(3):581-9.