N 1 , N 11 -Diethylnorspermine tetrahydrochloride

Name N 1 , N 11 -Diethylnorspermine tetrahydrochloride
Supplier Tocris Bioscience
Catalog 4523
Prices $139.00, $585.00
Sizes 10 mg, 50 mg
Function Type Inducer
Cas Number 156886-85-0
Chemical Name N,N'-bis[3-(Ethylamino)propyl]-1,3-propanediaminetetrahydrochloride
Formula C13H32N4.4HCl
Molecular Weight 390.27
Description Highly potent inducer of spermidine/spermine N 1 -acetyltransferase, able to increase enzyme activity 200-1000 fold.
Supplier Page Shop

Product References

Characterization of human spermidine/spermine N1-acetyltransferase purified from - Characterization of human spermidine/spermine N1-acetyltransferase purified from

Libby PR, Ganis B, Bergeron RJ, Porter CW. Arch Biochem Biophys. 1991 Feb 1;284(2):238-44.

Antitumor activity of N,N'-bis(ethyl)spermine homologues against human MALME-3 - Antitumor activity of N,N'-bis(ethyl)spermine homologues against human MALME-3

Bernacki RJ, Bergeron RJ, Porter CW. Cancer Res. 1992 May 1;52(9):2424-30.

Antitumor activity of N1,N11-bis(ethyl)norspermine against human melanoma - Antitumor activity of N1,N11-bis(ethyl)norspermine against human melanoma

Porter CW, Bernacki RJ, Miller J, Bergeron RJ. Cancer Res. 1993 Feb 1;53(3):581-6.

Structural basis for differential induction of spermidine/spermine - Structural basis for differential induction of spermidine/spermine

Fogel-Petrovic M, Kramer DL, Vujcic S, Miller J, McManis JS, Bergeron RJ, Porter CW. Mol Pharmacol. 1997 Jul;52(1):69-74.