Dihydro- β -erythroidine hydrobromide

Name Dihydro- β -erythroidine hydrobromide
Supplier Tocris Bioscience
Catalog 0884
Prices $179.00, $745.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 29734-68-7
Chemical Name (2S,13bS)-2-Methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-benzo[i]pyrano[3,4-g]indolizin-12-onehydrobromide
Formula C16H21NO3.HBr
Molecular Weight 356.26
Purity >98 %
Description Competitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α 4 receptor subunit (IC 50 values are 0.19 and 0.37 μ M for α 4 β 4 and α 4 β 2 receptors respectively). Antagonizes behavioral effects of nicotine in vivo .
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Product References

Binding of the nicotinic cholinergic antagonist, dihydro-beta-erythroidine, to - Binding of the nicotinic cholinergic antagonist, dihydro-beta-erythroidine, to

Williams M, Robinson JL. J Neurosci. 1984 Dec;4(12):2906-11.

In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic - In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic

Damaj MI, Welch SP, Martin BR. Psychopharmacology (Berl). 1995 Jan;117(1):67-73.

Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal - Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal

Harvey SC, Maddox FN, Luetje CW. J Neurochem. 1996 Nov;67(5):1953-9.