Diltiazem hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 0481
• Prices: $95.00
• Sizes: 1 g
• Function Type: Inhibitor
• Cas Number: 33286-22-5
• Chemical Name: (2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-onehydrochloride
• Formula: C22H26N2O4S.HCl
• Molecular Weight: 450.98
• Purity: >99 %
• Description: Antihypertensive and cardioprotective agent; an inhibitor of L-type Ca 2+ channels.

Product References

Effects of diltiazem on bioenergetics, K+ gradients, and free cytosolic Ca2+ - Effects of diltiazem on bioenergetics, K+ gradients, and free cytosolic Ca2+

Dagani F, Feletti F, Canevari L. J Neurochem. 1989 Nov;53(5):1379-89.

Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje - Block of P-type Ca2+ channels in freshly dissociated rat cerebellar Purkinje

Ishibashi H, Yatani A, Akaike N. Brain Res. 1995 Oct 9;695(1):88-91.

Inhibition of nicotinic receptor-mediated responses in bovine chromaffin cells by - Inhibition of nicotinic receptor-mediated responses in bovine chromaffin cells by

Gandia L, Villarroya M, Sala F, Reig JA, Viniegra S, Quintanar JL, Garcia AG, Gutierrez LM. Br J Pharmacol. 1996 Jul;118(5):1301-7.

Molecular mechanism of diltiazem interaction with L-type Ca2+ channels. - Molecular mechanism of diltiazem interaction with L-type Ca2+ channels.

Kraus RL, Hering S, Grabner M, Ostler D, Striessnig J. J Biol Chem. 1998 Oct 16;273(42):27205-12.