DiMNF

• Supplier: Tocris Bioscience
• Catalog: 4640
• Prices: $165.00, $685.00
• Sizes: 10 mg, 50 mg
• Function Type: Modulator
• Cas Number: 14756-24-2
• Chemical Name: 2-(3,4-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one
• Formula: C21H16O4
• Molecular Weight: 332.35
• Purity: >99 %
• Description: Selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). Suppresses expression of CD55 and CD46 induced by IL-1 β in an inflammatory tumor cell microenvironment; exhibits no effect on basal CD55 or CD46 expression.

Product References

Suppression of cytokine-mediated complement factor gene expression through - Suppression of cytokine-mediated complement factor gene expression through

Murray IA, Flaveny CA, Chiaro CR, Sharma AK, Tanos RS, Schroeder JC, Amin SG, Bisson WH, Kolluri SK, Perdew GH. Mol Pharmacol. 2011 Mar;79(3):508-19.

Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor - Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor

Labrecque MP, Takhar MK, Hollingshead BD, Prefontaine GG, Perdew GH, Beischlag TV. PLoS One. 2012;7(1):e29545.

Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 - Selective aryl hydrocarbon receptor modulator-mediated repression of CD55

Narayanan GA, Murray IA, Krishnegowda G, Amin S, Perdew GH. J Pharmacol Exp Ther. 2012 Aug;342(2):345-55.