DMAB-anabaseine dihydrochloride

Name DMAB-anabaseine dihydrochloride
Supplier Tocris Bioscience
Catalog 4378
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 154149-38-9
Chemical Name 4-[(5,6-Dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethylbenzenaminedihydrochloride
Formula C19H21N3.2HCl
Molecular Weight 364.32
Purity >98 %
Description Partial agonist at α 7-containing neuronal nicotinic receptors and antagonist at α 4 β 2 and other nicotinic receptors. Displays specific cognition-enhancing effects; improves long-term memory in rats.
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Product References

Improved learning and memory in aged rats with chronic administration of the - Improved learning and memory in aged rats with chronic administration of the

Arendash GW, Sengstock GJ, Sanberg PR, Kem WR. Brain Res. 1995 Mar 20;674(2):252-9.

Anabaseine is a potent agonist on muscle and neuronal - Anabaseine is a potent agonist on muscle and neuronal

Kem WR, Mahnir VM, Papke RL, Lingle CJ. J Pharmacol Exp Ther. 1997 Dec;283(3):979-92.

Selective alpha7-nicotinic agonists normalize inhibition of auditory response in - Selective alpha7-nicotinic agonists normalize inhibition of auditory response in

Stevens KE, Kem WR, Mahnir VM, Freedman R. Psychopharmacology (Berl). 1998 Apr;136(4):320-7.