| Name | DMNB |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1481 |
| Prices | $59.00, $199.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 20357-25-9 |
| Chemical Name | 4,5-Dimethoxy-2-nitrobenzaldehyde |
| Formula | C9H9NO5 |
| Molecular Weight | 211.15 |
| Purity | >98 % |
| Description | Inhibitor of DNA-dependent protein kinase (DNA-PK) (IC 50 = 15 μ M), an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells. Displays 100-fold higher potency than its analog vanillin and does not affect PKC activity. Produces lethal effects on cisplatin-treated D5037 cells upon continuous exposure. |
| Supplier Page | Shop |