| Name | Dolasetron mesylate |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 2643 |
| Prices | $75.00, $315.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 115956-13-3 |
| Chemical Name | 3-Oxooctahydro-2,6-methano-2H-quinolizin-8-yl1H-indole-3-carboxylatemethanesulfonate |
| Formula | C19H20N2O3.CH3SO3H |
| Molecular Weight | 420.48 |
| Purity | >99 % |
| Description | Potent and selective 5-HT 3 receptor antagonist (pIC 50 = 7.55). Exhibits 200-fold selectivity for 5-HT 3 over 5-HT 1A , 5-HT 1B and 5-HT 2 receptors, and a range of other GPCRs. Blocks the 5-HT-elicited von Bezold-Jarisch reflex in rats and suppresses cisplatin -induced vomiting in ferrets. |
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