Domoic acid

• Supplier: Tocris Bioscience
• Catalog: 3375
• Prices: $165.00, $685.00
• Sizes: 1 mg, 5 mg
• Function Type: Agonist
• Cas Number: 14277-97-5
• Chemical Name: (2S,3S,4R,5'R)-2-Carboxy-4-(5'-carboxy-1'-methyl-1Z,3E-hexadienyl)-3-pyrrolidineaceticacid
• Formula: C15H21NO6
• Molecular Weight: 311.33
• Purity: >95 %
• Description: Kainate receptor agonist. More potent and possibly more selective than kainate at kainate receptors, as demonstrated in electrophysiological studies.

Product References

The primary afferent depolarizing action of kainate in the rat. - The primary afferent depolarizing action of kainate in the rat.

Agrawal SG, Evans RH. Br J Pharmacol. 1986 Feb;87(2):345-55.

Domoic acid, the alleged "mussel toxin," might produce its neurotoxic effect - Domoic acid, the alleged "mussel toxin," might produce its neurotoxic effect

Debonnel G, Beauchesne L, de Montigny C. Can J Physiol Pharmacol. 1989 Jan;67(1):29-33.

The activation of glutamate receptors by kainic acid and domoic acid. - The activation of glutamate receptors by kainic acid and domoic acid.

Hampson DR, Manalo JL. Nat Toxins. 1998;6(3-4):153-8.