Doxycycline hyclate

• Supplier: Tocris Bioscience
• Catalog: 2252
• Prices: $49.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 24390-14-5
• Chemical Name: (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamidehydrochloridehemiethanolatehemihydrate
• Formula: C22H24N2O8.HCl.0.5C2H6O.0.5H2O
• Molecular Weight: 512.94
• Description: Broad-spectrum antibiotic and MMP inhibitor; tetracycline derivative. Increases and promotes smooth muscle cell adhesion; inhibits proliferation and migration. Protects the microvasculature by inhibiting plasminogen systems.

Product References

Doxycycline alters vascular smooth muscle cell adhesion, migration, and - Doxycycline alters vascular smooth muscle cell adhesion, migration, and

Franco C, Ho B, Mulholland D, Hou G, Islam M, Donaldson K, Bendeck MP. Am J Pathol. 2006 May;168(5):1697-709.

Doxycycline inhibits MMPs via modulation of plasminogen activators in focal - Doxycycline inhibits MMPs via modulation of plasminogen activators in focal

Burggraf D, Trinkl A, Dichgans M, Hamann GF. Neurobiol Dis. 2007 Mar;25(3):506-13. Epub 2006 Dec 12.

A drug-inducible transgenic system for direct reprogramming of multiple somatic - A drug-inducible transgenic system for direct reprogramming of multiple somatic

Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R. Nat Biotechnol. 2008 Aug;26(8):916-24.