DQP 1105

Name DQP 1105
Supplier Tocris Bioscience
Catalog 2168
Prices $175.00, $709.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 380560-89-4
Chemical Name 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoicacid
Formula C29H24BrN3O4
Molecular Weight 558.42
Purity >97 %
Description Noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC 50 values are 2.7, 8.5, 121, 153, 198 and 206 μ M, respectively). Reduces frequency of channel opening.
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